The Impact of a Mediterranean Dietary on the Variables Linked to an increased likelihood of Cardiac Diseases
DOI:
https://doi.org/10.56294/hl2025613Keywords:
Mediterranean diet, risk factor, cohort, cardiovascular disease (CVD), middle-aged peopleAbstract
The Mediterranean eating routine is a good dieting plan. In the Mediterranean region, few prospective studies examine the association between these dietary model and nonfatal cardiovascular proceedings. It monitored 127 initially healthy individuals for four years. The participants in this research were candidates from universities throughout the who were enrolled in a prospective cohort investigation. The baseline diet was assessed using a 130-item validated food frequency questionnaire. A 9-point scale was used to evaluate adherence to the Mediterranean diet. Medical record analysis verified incident clinical occurrences. Numerous studies have shown that individuals who adhered to the Mediterranean diet the best had fewer cardiovascular risks than those who did not. For every additional two focuses for cardiovascular, coronary illness, and cardiovascular disease (CVD), the changed risk proportions were separately. In healthy middle-aged people, the Mediterranean diet negatively correlates with the development of both fatal and non-fatal cardiovascular disease.
References
1. Morera LP, Marchiori GN, Medrano LA, Defagó MD. Stress, dietary patterns and cardiovascular disease: A mini-review. Frontiers in neuroscience. 2019 Nov 12;13:1226. https://doi.org/10.3389/fnins.2019.01226.
2. Lim CC, Hayes RB, Ahn J, Shao Y, Silverman DT, Jones RR, Thurston GD. Mediterranean diet and the association between air pollution and cardiovascular disease mortality risk. Circulation. 2019 Apr 9;139(15):1766-75. https://doi.org/10.1161/CIRCULATIONAHA.118.035742.
3. Bonaccio M, Costanzo S, Di Castelnuovo A, Persichillo M, Magnacca S, De Curtis A, Cerletti C, Donati MB, de Gaetano G, Iacoviello L, Moli-sani Study Investigators. Ultra-processed food intake and all-cause and cause-specific mortality in individuals with cardiovascular disease: the Moli-sani Study. European Heart Journal. 2022 Jan 14;43(3):213-24. https://doi.org/10.1093/eurheartj/ehab783.
4. Picard K, Senior PA, Perez SA, Jindal K, Richard C, Mager DR. Low Mediterranean Diet scores are associated with reduced kidney function and health related quality of life but not other markers of cardiovascular risk in adults with diabetes and chronic kidney disease. Nutrition, Metabolism and Cardiovascular Diseases. 2021 May 6;31(5):1445-53. https://doi.org/10.1016/j.numecd.2021.02.002.
5. Gutierrez‐Mariscal FM, Cardelo MP, de La Cruz S, Alcala‐Diaz JF, Roncero‐Ramos I, Guler I, Vals‐Delgado C, López‐Moreno A, Luque RM, Delgado‐Lista J, Perez‐Martinez P. Reduction in circulating advanced glycation end products by mediterranean diet is associated with increased likelihood of type 2 diabetes remission in patients with coronary heart disease: from the cordioprev study. Molecular Nutrition & Food Research. 2021 Jan;65(1):1901290. https://doi.org/10.1002/mnfr.201901290.
6. Han Y, Zeng H, Jiang H, Yang Y, Yuan Z, Cheng X, Jing Z, Liu B, Chen J, Nie S, Zhu J. CSC expert consensus on principles of clinical management of patients with severe emergent cardiovascular diseases during the COVID-19 epidemic. Circulation. 2020 May 19;141(20):e810-6. https://doi.org/10.1161/CIRCULATIONAHA.120.047011.
7. Rana MN, Neeland IJ. Adipose tissue inflammation and cardiovascular disease: an update. Current Diabetes Reports. 2022 Jan;22(1):27-37. https://doi.org/10.1007/s11892-021-01446-9.
8. Rahimlou M, Grau N, Banaie-Jahromi N, Taheri M, Khosravi A, Mavrommatis Y, Mohammadifard N. Association of adherence to the dietary approach to stop hypertension and Mediterranean diets with blood pressure in a non-hypertensive population: Results from Isfahan Salt Study (ISS). Nutrition, Metabolism and Cardiovascular Diseases. 2022 Jan 1;32(1):109-16. https://doi.org/10.1016/j.numecd.2021.09.029 .
9. Diez J, Bilal U, Franco M. Unique features of the Mediterranean food environment: Implications for the prevention of chronic diseases Rh: Mediterranean food environments. European Journal of Clinical Nutrition. 2019 Jul;72(Suppl 1):71-5. https://doi.org/10.1038/s41430-018-0311-y.
10. Tierney A, Lordan R, Tsoupras A, Zabetakis I. Diet and cardiovascular disease: The mediterranean diet. InThe impact of nutrition and statins on cardiovascular diseases 2019 Jan 1 (pp. 267-288). Academic Press. https://doi.org/10.1016/B978-0-12-813792-5.00008-2.
11. Urpi-Sarda M, Casas R, Sacanella E, Corella D, Andrés-Lacueva C, Llorach R, Garrabou G, Cardellach F, Sala-Vila A, Ros E, Ruiz-Canela M. The 3-year effect of the Mediterranean diet intervention on inflammatory biomarkers related to cardiovascular disease. Biomedicines. 2021 Jul 22;9(8):862. https://doi.org/10.3390/biomedicines9080862.
12. Salinero-Fort MA, Andrés-Rebollo FS, Cárdenas-Valladolid J, Méndez-Bailón M, Chico-Moraleja RM, de Santa Pau EC, Jiménez-Trujillo I, Gomez-Campelo I, de Burgos Lunar C, de Miguel-Yanes JM. Cardiovascular risk factors associated with acute myocardial infarction and stroke in the MADIABETES cohort. Scientific reports. 2021 Jul 27;11(1):15245. https://doi.org/10.1038/s41598-021-94121-8.
13. Hosking DE, Eramudugolla R, Cherbuin N, Anstey KJ. MIND not Mediterranean diet related to 12-year incidence of cognitive impairment in an Australian longitudinal cohort study. Alzheimer's & Dementia. 2019 Apr 1;15(4):581-9. https://doi.org/10.1016/j.jalz.2018.12.011.
14. Serra-Majem L, Roman-Vinas B, Sanchez-Villegas A, Guasch-Ferre M, Corella D, La Vecchia C. Benefits of the Mediterranean diet: Epidemiological and molecular aspects. Molecular aspects of medicine. 2019 Jun 1;67:1-55. https://doi.org/10.1016/j.mam.2019.06.001.
15. Ding D, Van Buskirk J, Nguyen B, Stamatakis E, Elbarbary M, Veronese N, Clare PJ, Lee IM, Ekelund U, Fontana L. Physical activity, diet quality and all-cause cardiovascular disease and cancer mortality: a prospective study of 346 627 UK Biobank participants. British journal of sports medicine. 2022 Oct 1;56(20):1148-56. https://doi.org/10.1136/bjsports-2021-105195.
16. Martínez-González MA, Gea A, Ruiz-Canela M. The Mediterranean diet and cardiovascular health: A critical review. Circulation research. 2019 Mar 1;124(5):779-98. https://doi.org/10.1161/CIRCRESAHA.118.313348.
17. Li J, Guasch-Ferré M, Chung W, Ruiz-Canela M, Toledo E, Corella D, Bhupathiraju SN, Tobias DK, Tabung FK, Hu J, Zhao T. The Mediterranean diet, plasma metabolome, and cardiovascular disease risk. European heart journal. 2020 Jul 21;41(28):2645-56. https://doi.org/10.1093/eurheartj/ehaa209.
18. Mendonça RD, Carvalho NC, Martin-Moreno JM, Pimenta AM, Lopes AC, Gea A, Martinez-Gonzalez MA, Bes-Rastrollo M. Total polyphenol intake, polyphenol subtypes and incidence of cardiovascular disease: The SUN cohort study. Nutrition, Metabolism and Cardiovascular Diseases. 2019 Jan 1;29(1):69-78. https://doi.org/10.1016/j.numecd.2018.09.012.
19. Rosato V, Temple NJ, La Vecchia C, Castellan G, Tavani A, Guercio V. Mediterranean diet and cardiovascular disease: a systematic review and meta-analysis of observational studies. European journal of nutrition. 2019 Feb 1;58:173-91. https://doi.org/10.1007/s00394-017-1582-0.
20. Andreu-Reinón ME, Chirlaque MD, Gavrila D, Amiano P, Mar J, Tainta M, Ardanaz E, Larumbe R, Colorado-Yohar SM, Navarro-Mateu F, Navarro C. Mediterranean diet and risk of dementia and Alzheimer’s disease in the EPIC-Spain dementia cohort study. Nutrients. 2021 Feb;13(2):700. https://doi.org/10.3390/nu13020700.
21. Fresán U, Martínez-González MA, Sabaté J, Bes-Rastrollo M. Global sustainability (health, environment and monetary costs) of three dietary patterns: results from a Spanish cohort (the SUN project). BMJ open. 2019 Feb 1;9(2):e021541. https://doi.org/10.1136/bmjopen-2018-021541.
22. Sánchez-Sánchez ML, García-Vigara A, Hidalgo-Mora JJ, García-Pérez MÁ, Tarín J, Cano A. Mediterranean diet and health: A systematic review of epidemiological studies and intervention trials. Maturitas. 2020 Jun 1;136:25-37. https://doi.org/10.1016/j.maturitas.2020.03.008s.
23. Battino M, Forbes-Hernández TY, Gasparrini M, Afrin S, Cianciosi D, Zhang J, Manna PP, Reboredo-Rodríguez P, Varela Lopez A, Quiles JL, Mezzetti B. Relevance of functional foods in the Mediterranean diet: the role of olive oil, berries and honey in the prevention of cancer and cardiovascular diseases. Critical reviews in food science and nutrition. 2019 Mar 26;59(6):893-920. https://doi.org/10.1080/10408398.2018.1526165.
24. Veronese N, Notarnicola M, Cisternino AM, Inguaggiato R, Guerra V, Reddavide R, Donghia R, Rotolo O, Zinzi I, Leandro G, Tutino V. Trends in adherence to the Mediterranean diet in South Italy: A cross sectional study. Nutrition, Metabolism and Cardiovascular Diseases. 2020 Mar 9;30(3):410-7. https://doi.org/10.1016/j.numecd.2019.11.003.
25. Alvarez-Alvarez I, Toledo E, Lecea O, Salas-Salvadó J, Corella D, Buil-Cosiales P, Zomeño MD, Vioque J, Martinez JA, Konieczna J, Barón-López FJ. Adherence to a priori dietary indexes and baseline prevalence of cardiovascular risk factors in the PREDIMED-Plus randomised trial. European Journal of Nutrition. 2020 Apr;59:1219-32. https://doi.org/10.1007/s00394-019-01982-x.
26. Liu X, Zheng Y, Guasch-Ferré M, Ruiz-Canela M, Toledo E, Clish C, Liang L, Razquin C, Corella D, Estruch R, Fito M. High plasma glutamate and low glutamine-to-glutamate ratio are associated with type 2 diabetes: case-cohort study within the PREDIMED trial. Nutrition, Metabolism and Cardiovascular Diseases. 2019 Oct 1;29(10):1040-9. https://doi.org/10.1016/j.numecd.2019.06.005.
27. Aoun C, Papazian T, Helou K, El Osta N, Khabbaz LR. Comparison of five international indices of adherence to the Mediterranean diet among healthy adults: similarities and differences. Nutrition research and practice. 2019 Aug 1;13(4):333-43. https://doi.org/10.4162/nrp.2019.13.4.333.
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Copyright (c) 2025 Kusum Yadav, Blessing Nima Xaviour Selvaraj, Rashmi Mishra, Amit Kumar, Bharat Bhushan, Karan Pandre (Author)
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