Actinic Keratosis: Diagnosis and Management

Authors

  • Anjna Rani Noida Institute of Engineering and Technology Pharmacy Institute, Greater Noida, Uttar Pradesh, India Author https://orcid.org/0000-0002-7575-7580
  • Manish Nagpal Chitkara Centre for Research and Development, Chitkara University, Himachal Pradesh-174103 India Author https://orcid.org/0009-0000-9823-5251
  • Ankit Punia Centre of Research Impact and Outcome, Chitkara University, Rajpura- 140417, Punjab, India Author https://orcid.org/0009-0003-6508-2596
  • Kukatla Tejesh Centre for Multidisciplinary Research, Anurag University, Hyderabad, Telangana, India Author https://orcid.org/0009-0003-3330-1918
  • Liza Mohapatra Department of Skin & VD, IMS and SUM Hospital, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India Author https://orcid.org/0000-0002-2658-3844
  • Rahul Patil Department of Medicine, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth “Deemed to be University, Taluka-Karad, Dist-Satara, Pin-415 539, Maharashtra, India Author

DOI:

https://doi.org/10.56294/hl2025596

Keywords:

High-Frequency Ultrasound (HFUS), Non-invasive imaging, Non-Melanoma Skin Cancer (NMSC), Actinic Keratoses (AK)

Abstract

Actinic Keratoses (AKs) develop at a rate of up to 20% during ten years thus making them one of the most common Cutaneous Cancer (CC) types and potential developments into Squamous Cell Carcinoma (SCC). The diagnostic procedures of clinical examination and histology fail to identify subclinical Actinic Keratoses so the research requires novel non-invasive imaging alternatives. High-Frequency Ultrasound (HFUS) demonstrates value in AK diagnosis because it provides detailed real-time visualization of multiple skin levels. A comparison of HFUS diagnostic capabilities against standard histological assessment exists in this research. A clinical checkup alongside HFUS imaging and histological testing were conducted on 150 patients who displayed at least one case of AK. Through its precision evaluation with histological results and its minimal detection errors totaling just 3.5%, HFUS successfully detected AKs in 96.5% of studied cases. Medical professionals can use HFUS with success as an alternative to standard biopsy practices because it identifies AK early without surgery and provides enhanced diagnostic accuracy in standard clinical settings.

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Published

2025-08-05

How to Cite

1.
Rani A, Nagpal M, Punia A, Tejesh K, Mohapatra L, Patil R. Actinic Keratosis: Diagnosis and Management. Health Leadership and Quality of Life [Internet]. 2025 Aug. 5 [cited 2025 Aug. 30];4:596. Available from: https://hl.ageditor.ar/index.php/hl/article/view/596