Immuno-nutritional and insulin-resistance markers associated with severe perioperative complications after cardiac surgery
DOI:
https://doi.org/10.56294/hl2024.468Keywords:
Biomolecular markers, immuno-inflammation, insulin resistance, cardiovascular surgeryAbstract
Introduction: The progress of cardiac surgery that has been parallel to technological development has not been able to sufficiently counteract the high morbidity and mortality of cardiovascular surgical patients and their high costs; for this reason, the search for markers that can predict adverse effects and post-surgical complications in time and facilitate a better evaluation of these patients continues.
Objective: to evaluate the degree of association of new immuno-nutritional and insulin-resistance biomolecular markers with the appearance of serious perioperative complications.
Methods: An ambispective cohort study was carried out on patients who underwent major cardiovascular surgery between January 1, 2019 and December 31, 2023 at the Cardiocentro of Santiago de Cuba, who met inclusion criteria.
Results: A significant association was found between immuno-nutritional and insulin resistance biomarkers and severe perioperative complications: triglyceride-glycemia index (p=0.000 RR 5.23), leuko-glycemic index (p=0.000 RR 7.76), nutritional prognostic index (p=0.004 RR 2.56), albumin/globulin ratio (p=0.050 RR 0.338).
Conclusions: A close link is demonstrated between the new biomarkers selected and severe perioperative complications, so their inclusion in the preoperative assessment could facilitate earlier monitoring, diagnosis and treatment of complications and reduce morbidity and mortality in these patients
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Copyright (c) 2024 Germán el Río Caballero, Lucía Nivia Turro Mesa, Del Río Mesa, Rita María Mesa Valiente, Eloy Turro Caró (Author)
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