Theoretical foundations on risk factors predictive of mortality due to acute heart failure
DOI:
https://doi.org/10.56294/hl2024.428Keywords:
acute heart failure, prediction, mortality, cardiovascular diseases, risk factorsAbstract
Introduction: Acute heart failure is a public health problem. It is necessary to predict the risk of mortality in these patients.
Objective: to systematize the theoretical references that support the predictive risk factors for mortality due to acute heart failure.
Development: different researchers approach the prediction process from different areas of knowledge, at the national and international level, and theoretical positions related to the topic are adopted.
Conclusions: the systematization carried out on the prediction of mortality due to acute heart failure allowed us to establish an approach to the theoretical references that support the topic.
References
1. Libby P, Zipes DP, Bonow RO, Mann DL, Tomaselli GF. Braunwald `s Heart Disease. A textbook of cardiovascular Medicine. 12 ed. Philadelphia: Elsevier Saunders; 2022. P. 1-1902.
2. Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP et al. Heart Disease and Stroke Statistics-2020 Update: A Report from the American Heart Association. Circulation. 2020 [cited 2021 may 02]; 141 (9): e139-e596. Disponible en : https://doi.org/10.1161/CIR.0000000000000757
3. Sthahli BE, Roffi M, Eberli FR, Rickli H, Erne P, Maggorini M et al. Temporal trends in in-hospital complications of acute coronary syndromes: Insights from the nationwide AMIS Plus registry. Int J of Cardiol. 2020 [cited 2021 may 02]; 313: 16-24 DOI: https://doi.org/10.1016/j.ijcard.2020.04.003.
4. Abreu D, Sousa P, Matias-Dias C, Pinto F. Impact of public health initiatives on acute coronary syndrome fatality rates in Portugal. Rev Port Cardiol. 2020 [cited 2023 jun 2];39 (1):27-34. DOI: 10.1016/j.repc.2019.05.010
5. Wang TKM, Grey C, Jiang Y, Jackson RT, Kerr AJ. Nationwide trends in acute coronary syndrome by subtype in New Zealand 2006-2016. Heart. 2020 Feb [cited 2021 marzo 02];106(3):221-227. DOI: 10.1136/heartjnl-2019-315655.
6. Cuba. Ministerio de Salud Pública. Dirección de Registros Médicos y Estadística de Salud. Anuario Estadístico de Salud 2023. La Habana: MINSAP; 2024 [2024 mayo 25]. Disponible en: https://salud.msp.gob.cu/wp-content/Anuario/anuario2022.pdf
7. Cuba. Ministerio de Salud Pública. Dirección de Registros Médicos y Estadística de Salud. Anuario Estadístico de Salud 2021. La Habana: MINSAP; 2022 [2024 mayo 25]. Disponible en: https://salud.msp.gob.cu/wp-content/Anuario/anuario_2020_edici%C3%B3n_2021.pdf
8. Chávez-Alfonso Christian Osmar, Centurión Osmar Antonio. Mecanismos fisiopatológicos, neurohormonales y objetivos terapéuticos en la insuficiencia cardiaca aguda. Mem. Inst. investigando Cienc. Salud. 2019 Dic [citado 2023 Feb 02]; 17(3):82-96.Disponible en: https://doi.org/10.18004/mem.iics/9528/2019.017.03.82-096.
9. Valdivia-Marchal M, Zambrana-Luque JL, Girela-Lopez E, Font-Ugalde P, Salcedo-Sánchez MC, Zambrana-García JL. Factores predictores de mortalidad en pacientes hospitalizados por insuficiencia cardiaca. Anales Sis San Navarra [Internet]. 2020 Abr [citado 2023 Feb 02]; 43(1):57-67.DOI: https://dx.doi.org/10.23938/assn.0753.
10. Lancellotti P, Ancion A, Magne J, Ferro G, Piérard LA. Elevated heart rate at 24-36 h after admission and in-hospital mortality in acute in non-arrhythmic heart failure. Int J Cardiol. 2015 [cited 2023 jun 3]; 182: 426-430.DOI: 10.1016/j.ijcard.2015.01.027
11. Turcato G, Sanchis GF, Cervellin G, Zorzi E, Sivero V, Salvagno GL et al. Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure. J Med Biochem. 2019 [cited 2023 jun 3]; 38(4): 452–460, DOI: 10.2478/jomb-2018-0044
12. LaMarca B, Alexander BT. Sex differences in cardiovascular physiology and pathophysiology.1 ed. Elsevier Science. 2019 jun [cited 2023 jun 3].392.Disponible en: https://doi.org/10.1016/C2014-0-02648-2
13. Monteiro JGM, de Oliveira CT, Filho DCS. Hematological parameters as prognostic biomarkers in patients with cardiovascular diseases. Curr Cardiol Rev. 2019 Feb [cited 2023 jun 3]; 15(4): 274-282. DOI: 10.2174/1573403X15666190225123544
14. Boralkar KA, Kobayashi Y, Amsallem M, Ataam JA, Moneghetti KJ, Cauwenberghs N et al. Value of neutrophil to lymphocyte ratio and its trajectory in patients hospitalized with acute heart failure and preserved ejection fraction. Am J Cardiol. 2020 [cited 2023 jun 3];125(2):229-235. DOI: 10.1016/j.amjcard.2019.10.020
15. Garcia PE, Soler SMJ, Cerda GP, Zamora ML, Baeza MC, Grau DJ, Padilla NI. Prognostic Value of Hematological Inflammatory Markers in Patients with Pleural Effusion Due to Heart Failure. Clin Lab. 2020 Mar 1 [cited 2023 jun 20]; 66(3). DOI: 10.7754/Clin.Lab.2019.190707
16. Liu L, Gong B, Wang W, Xu K, Wang K and Song G. Association between haemoglobin, albumin, lymphocytes, and platelets and mortality in patients with heart failure. ESC Heart Fail. 2024 Apr;11(2): 1051–1060.DOI: 10.1002/ehf2.14662
17. Mezquía PN, Soler MC, Tamargo BTO, Olmo MJ. Aplicación de un índice pronóstico de mortalidad en pacientes con insuficiencia cardiaca aguda. Rev Cubana Med.2016 Dic [citado 2022 Dic 29]; 55(4):287-296.Disponible en: http://scielo.sld.cu/scielo.php?Script=sci_arttext&pid=S0034-75232016000400003&Ing=es
18. Mezquía N., Soler C., Tamargo T., Olmo J. Valor de las variables clínicas para el pronóstico de la mortalidad por insuficiencia cardíaca aguda. Rev Cubana Med. 2015 Dic [citado 2024 Mar 3]; 54(4). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75232015000400004&Ing=es
19. McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Bohm M et al. Guías ESC 2021 para el diagnóstico y tratamiento de la insuficiencia cardíaca aguda y crónica. Rev Esp Cardiol [Internet]. 2022 jun [citado 2022 Mar 9];75(6):523.DOI: 10.1016/j.recesp.2021.11.027
20. Araiza Garaygordobil D, Illescas González E, Cossío Aranda JE, Kuri Alfaro J, Guadalajara Boo JF. El valor clínico del examen físico en cardiología: revisión de la evidencia. Arch. Cardiol. Méx. 2017[citado 2019 mayo 9] ;87(4):265-269. DOI: 10.1016/j.acmx.2017.06.002
21. Echazarreta FD. Abordaje diagnóstico de la insuficiencia cardíaca. Insuf Card.2008 dic [citado 2023 jun 14];3(4):196-204.Disponible en: http://www.redalyc.org/articulo.oa?id=321927784006
22. Collins SP, Jenkins CA, Harrell FE, Liu D, Miller KF, Lindsell CJ et al .Identification of Emergency Departament Patients With Acute Heart Failure at Low Risk for 30-days Adverse Events: The STRATIFY Decision Tool. JACC. Heart Failure.2015 [cited 2023 jun 20]; 3(10): 737-747. Disponible en: https://doi.org/10.1016/j.jchf.2015.05.007
23. Appiani Franco. Vigilancia de la descongestión en la insuficiencia cardiaca aguda. Rev méd Chile [Internet]. 2022 Abr [citado 2023 Feb 02]; 150(4):493-504.Disponible en:http://www.scielo.cl/scielo.php? script=sci_arttext&pid=S0034-98872022000400493&Ing=en. https://dx.doi.org/10.4067/S0034-98872022000400493.
24. Wang XY, Zhang F, Zhang C, Zheng LR, Yang J. The Biomarkers for Acute Myocardial Infarction and Heart Failure. BioMed Research International. 2020 [cited 2021 marzo 02] (5):1-14.Disponible en https://doi.org/10.1155/2020/2018035
25. Chuda A, Banach M, Maciejewski M, Bielecka-Dabrowa A. Role of confirmed and potential predictors of an unfavorable outcome in heart failure in everyday clinical practice. Ir J Med Sci.2022 [cited 2023 jun 20]; 191(1):213–227. Disponible en https://doi.org/10.1007/s11845-020-02477-z
26. Felker GM, Anstrom KJ, Adams KF, Ezekowitz JA, Fiuzat M, Houston-Miller N et al. Effect of natriuretic peptide–guided therapy on hospitalization or cardiovascular mortality in high-risk patients with heart failure and reduced ejection fraction: A randomized clinical trial. JAMA – J Am Med Assoc. 2017 [cited 2023 jun 20]; 318(8):713-720. DOI: 10.1001/jama.2017.10565
27. Harjola VP, Parissis J, Brunner-La Rocca HP, Celutkiene J, Chioncel O, Collins SP et al. Comprehensive in-hospital monitoring in acute heart failure: applications for clinical practice and future directions for research. A statement from the Acute Heart Failure Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). Eur J Heart Fail [Internet]. 2018 Jul 1 [citado 2022 Feb 22]; 20(7):1081–1099. Available from: https://doi.org/10.1002/ejhf.1204
28. Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JGF, Coats AJS et al. Guía ESC 2016 sobre el diagnóstico y tratamiento de la insuficiencia cardiaca aguda y crónica. Rev Esp Cardiol. 2016 [cited 2023 jun 3];37 (27): 2129-2200. DOI: 10.1093/eurheartj/ehw128
29. Carbone S, Billingsley HE, Rodriguez-Miguelez P, Kirkman DL, Garten R, Franco RL et al .Lean mass abnormalities in heart failure: the role of sarcopenia, sarcopenic obesity, and cachexia. Curr Probl Cardiol. 2020 nov [cited 2023 jun 20]; 45(11). Available from: https://doi.org/10.1016/j.cpcardiol.2019.03.006
30. Belziti C, Garagoli F, Favini A, Chiabrando J., Barbagelata L, Denes J et al. Valor pronóstico de la presentación clínica en los síndromes de insuficiencia cardiaca aguda. Rev Argent Cardiol. [Internet]. 2019 Feb [citado 2023 may 02]; 87(1): 34-40.Disponible en: http://dx.doi.org/10.7775/rac.es.v87.i1.13871
31. Jacob J, Miró Ó, Herrero P, Martín-Sánchez FJ, Gil V, Tost J et al. Predicción de la mortalidad a muy corto plazo de los pacientes con insuficiencia cardiaca crónica agudizada: escala EAHFE-3D. Med Intensiva.2016 [citado 2023 junio 20]; 40(6):348-355. Available from: http://dx.doi.org/10.1016/j.medin.2015.07.013
32. Hollenberg SM, Warner Stevenson L, Ahmad T, Amin VJ, Bozkurt B, Butler J et al. 2019 ACC Expert Consensu Decision Pathway on Risk Assessment, Management, and Clinical Trajectory of Patients Hospitalized With Heart Failure: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2019 Oct 15 [cited 2023 jun 3]; 74(15):1966-2011. DOI: 10.1016/j.jacc.2019.08.001
33. Kawase T, Toyofuku M, Higashihara T, Okubo Y, Takahashi L, Kagawa Y, et al. Validation of lactate level as a predictor of early mortality in acute decompensated heart failure patients who entered intensive care unit. J Cardiol. 2015 [cited 2023 jun 20];65(2):165-170. DOI: 10.1016/j.jjcc.2014.05.006
34. Ílhan B, Bozdereli Berikol G, Dogan H, Bestemir A, Kaya A.The prognostic Accuracy of Get With The Guidelines-Heart Failure Score Alone and with Lactate Among Acute Symptomatic Heart Failure Patients: A Retrospective Cohort Study. Anatol J Cardiol.2024 apr 17 [cited 2023 jun 20] ; 28(6): 305-11.DOI:10.14744/ AnatolJCardiol.2024.4116
35. Rider I, Sorense M, Brady WJ, Gottlieb M, Benson S, Koyfman A et al. Disposition of acute decompensated heart failure from the emergency department: An evidence-based review. The American Journal of emergency medicine.2021 [cited 2023 jun 3];50: 459-465.Disponible en https://doi.org/10.1016/j.ajem.2021.08.070
36. Alonso Mendoza LA. Manejo diagnóstico y principales hallazgos en pacientes con insuficiencia cardíaca, ingresados al Servicio de Medicina Interna, HEODRA, León, durante 2017-2018. [Tesis]. León: Universidad Nacional Autonóma de Nicaragua; 2020. [acceso:21/06/2024].Disponible en: http://riul.unanleon.edu.ni:8080/jspui/handle/123456789/4835
37. Delcea C, Buzea CA, Dan GA. The neutrophil to lymphocyte ratio in heart failure: a comprehensive review. Rom. J. Intern Med. 2019 [cited 2023 jun 20]; 57(4):296–314. DOI: 10.2478/rjim-2019-0018
38. Xu N, Tang XF, Yao Y, Zhao X, Chen J, Gao Z et al. Predictive value of neutrophil to lymphocyte ratio in long-term outcomes of left main and/or three-vessel disease in patients with acute myocardial infarction. Catheter Cardiovasc Interv. 2018 [cited 2023 jun 20]; 91(S1):551–557. DOI: 10.1002/ccd.27495
39. Angkananard T, Anothaisintawee T, McEvoy M, Attia J , Thakkinstian A. Neutrophil Lymphocyte Ratio and Cardiovascular Disease Risk: A Systematic Review and Meta-Analysis. BioMed Research International. 2018 [cited 2023 jun 20]; 2018:1-11. Available from: https://doi.org/10.1155/2018/2703518
40. Rayes J, Bourne JH, Brill A, Watson SP. The dual role of platelet-innate immune cell interactions in thrombo-inflammation. Res Pract Thromb Haemost. 2019 Oct 17 [cited 2023 may 30]; 4(1):23-35. DOI: 10.1002/rth2.12266. eCollection 2020 Jan
41. Ferrucci L, Fabbri E. Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty. Nat Rev Cardiol. 2018 Sep [cited 2023 jun 3]; 15(9): 505–522.DOI: 10.1038/s41569-018-0064-2
42. Yura Y, Sano S, Walsh K. Clonal Hematopoiesis: A New Step Linking Inflammation to Heart Failure. J Am Coll Cardiol Basic Trans Science. 2020 [cited 2023 jun 3]; 5(2):196–207. DOI:10.1016/j.jacbts.2019.08.006
43. Milinkovic I, Polovina M, Simeunovic DS, Asˇanin M and Seferovic PM. Oxidative stress and inflammation in heart failure: The best is yet to come. Eur J Prev Cardiol. 2020 [cited 2023 jun 3];27(5) 490–493. DOI:10.1177/2047487319900294
44. Swirski FK, Nahrendorf M. Cardioimmunology: the immune system in cardiac homeostasis and disease. Nat Rev Immunol. 2018 [cited 2023 jun 3];18(12):733–744.Disponible en: https://doi.org/10.1038/s41577-018-0065-8
45. Murphy SP, Kakkar R, McCarthy CP, Januzzi JL. Inflammation in Heart Failure: JACC state-of-the Art Review. J Am Coll Cardiol. 2020 March [cited 2023 jun 3]; 75(11)1324-1340. DOI: 10.1016/j.jacc.2020.01.014
46. Ridker P, Libby P, MacFadyen JD, Thuren T, Ballantyne T Ch, Fonseca F et al. Modulation of the interleukin-6 signalling pathway and incidence rates of atherosclerotic events and all-cause mortality: analyses from the Canakinumab Anti-Inflammatory Thrombosis Outcomes Study (CANTOS). European Heart Journal. 2018 oct [cited 2023 jun 3]; 39(38), 3499–3507. DOI: 10.1093/eurheartj/ehy310
47. Cognasse F, Laradi S, Berthelot P, Bourlet T, Marotte H, Mismetti P et al. Platelet inflammatory response to stress. Front Immunol. 2019 June [cited 2023 jun 3]; 10:1478. DOI:10.3389/ fimmu.2019.01478
48. Budzianowski J, Pieszko K, Burchardt P, Rzeźniczak J, Hiczkiewicz J. The Role of Hematological Indices in Patients with Acute Coronary Syndrome. Disease Markers.2017 [cited 2023 jun 3];(9):1-9. Disponible en: https://doi.org/10.1155/2017/3041565.
49. Morici N, Cantoni S, Soriano F, Viola G, De Stefano V, Veas N et al. Relevance of complete blood count parameters in the assessment of acute coronary syndromes: a combined hematological and cardiological perspective. G Ital Cardiol. 2019 Dec [cited 2023 jun 3]; 20(12):694-705. DOI: 10.1714/3271.32379
50. Banks E, Joshy G, Korda RJ, Stavreski B, Soga K, Egger S, et al. Tobacco smoking and risk of 36 cardiovascular disease subtypes: fatal and non-fatal outcomes in a large prospective Australian study. BMC Medicine. 2019 [cited 2020 june 8]. Disponible en: https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-019-1351-4
51. Born MC, de Oliveira Azzolin K, Nogueira de Souza E. How long before hospital admission do the symptoms of heart failure decompensation arise? Rev. Lat Am Enfermagem. 2019 [cited 2023 june 20]; 27: e3119. Disponible en: https://www.scielo.br/j/rlae/a/f6kq7wXdPxYp3qLStzHLF5v/?lang=en&format=pdf
52. Andreadou I, Cabrera-Fuentes HA, Devaux Y, Frangogiannis NG, Frantz S, Guzik T et al. Immune cells as targets for cardioprotection: new players and novel therapeutic opportunities. Cardiovascular Research.2019 [cited 2023 june 20]; 115(7):1117–1130. DOI: 10.1093/cvr/cvz050
53. Budzianowski J, Pieszko K, Burchardt P, Rzeźniczak J, Hiczkiewicz J. The Role of Hematological Indices in Patients with Acute Coronary Syndrome. Disease Markers.2017 [cited 2023 jun 3];(9):1-9. Disponible en: https://doi.org/10.1155/2017/3041565.
54. Banks E, Joshy G, Korda RJ, Stavreski B, Soga K, Egger S, et al. Tobacco smoking and risk of 36 cardiovascular disease subtypes: fatal and non-fatal outcomes in a large prospective Australian study. BMC Medicine. 2019 [cited 2020 june 8]. Disponible en: https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-019-1351-4
55. Born MC, de Oliveira Azzolin K, Nogueira de Souza E. How long before hospital admission do the symptoms of heart failure decompensation arise? Rev. Lat Am Enfermagem. 2019 [cited 2023 june 20]; 27: e3119. Disponible en: https://www.scielo.br/j/rlae/a/f6kq7wXdPxYp3qLStzHLF5v/?lang=en&format=pdf
56. Angkananard T, Inthanoo T, Sricholwattana S, Rattanajaruskul N, Wongsoasu A, Roongsangmanoon, W. The predictive role of Neutrophil-to-Lymphocyte Ratio (NLR) and Mean Platelet Volume-to-Lymphocyte Ratio (MPVLR) for Cardiovascular Events in Adult Patients with Acute heart Failure. Mediators of inflammation.2021 [cited 2023 may 30];2021:12.Disponible en https://doi.org/10.1155/2021/6889733
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